They did a one-off with them at the Royal Albert Hall, was a nod to a joke about it in The Simpsons.
https://www.theguardian.com/music/article/2024/jul/10/hip-hop-band-cypress-hill-makes-1996-simpsons-joke-come-true-london-symphony-orchestra
Sadly it’s kinda standard for the Pyramid, they’re not too big on party starters on that stage, although occasionally one slips through.
If you want a party starter headliner West Holts usually provides and The Other Stage often does the job.
Happy to be proved otherwise, but I believe the days of having three top-tier headliners have gone. Gaga and Eminem maybe, but those acts that can sell out multiple stadiums at eye-watering prices will carry on doing that (unless they're friends of the Eavii, or really want to do it).